About William DePippo
Real estate executive with 20+ years of experience leading complex, multi-regional development projects for publicly traded Fortune 500 companies.
SVP of Real Estate Development
Deep expertise in life sciences, commercial development, strategic repositioning, infrastructure, entitlements, & master planning. Proven leader skilled in uniting cross-regional teams to drive financial, operational, & regulatory excellence from project inception to full occupancy.
William’s Expertise
Experience
With more than 20 years of executive-level leadership in real estate development and over $1.5 billion in assets under his direct oversight since 2020 alone, William Depippo has earned a reputation as one of the most trusted operators in commercial construction and strategic development. His impact spans the life sciences, biotech, residential, and mixed-use sectors—delivering iconic, award-winning spaces for some of the world’s leading developers and corporations.
Leadership
Currently Senior Vice President of Real Estate Development at Alexandria Real Estate Equities (ARE), Bill has been instrumental in shaping the built environments that power innovation across the U.S. East Coast. From the booming biotech corridors of Maryland and North Carolina to the urban complexity of Cambridge, MA, Bill has proven himself time and again as a leader who can deliver—on time, on budget, and above expectation.
Insider Knowledge
What distinguishes Bill isn’t just the size of his projects or the complexity he manages—it’s the journey that shaped him. Unlike many in his role, Bill did not enter the industry via a traditional MBA route. He earned his place by starting at the foundation—literally—as a construction worker. From those early days, he embraced a hands-on approach and immersed himself in every function within a well-established general contracting and construction management firm. This real-world experience, combined with a Bachelor of Science in History and Philosophy from Saint Joseph’s College, created a unique and pragmatic leadership style rooted in humility, grit, and cross-functional fluency.
Why Choose William
At ARE, Bill has led
the development of more than 11 million square feet of high-performance space over a decade. Key projects include the FujiFilm Diosynth and Beam Therapeutics campuses in North Carolina, the landmark ACLS-Shady Grove mega-campus in Maryland, and MilliporeSigma’s largest North American facility. These high-profile developments consistently meet LEED certification standards and are regularly recognized with industry awards for excellence in design, sustainability, and community impact.
In Cambridge, his influence
is no less significant. Bill played a leading role in the development and repositioning of multiple high-value projects including 399 Binney Street, 50 Rogers Street, and IBM’s regional headquarters at 75/125 Binney. His ability to reengineer fully permitted lab buildings, navigate entitlements, and manage large-scale sales to nationally recognized REITs illustrates both operational expertise and strategic foresight.
Bill is particularly adept
at managing risk and unlocking value. Whether modernizing infrastructure, repositioning underutilized assets, or developing actionable master plans for complex sites, his approach blends technical rigor with visionary thinking. He aligns design, development, and delivery to long-term market trends—ensuring scalability, compliance, and future-proof growth.
Peers and partners alike
regard him as a results-driven professional who never settles. He’s the leader brought in when the stakes are high, when clarity is needed, and when execution cannot fail. His personal mantra—“always try to be the best I can be”—is evident in the excellence he brings to every square foot he touches.
William Depippo’s career
stands as a masterclass in earned success. With his blend of on-the-ground experience, executive insight, and unwavering commitment to growth, he continues to set the standard for leadership in real estate development.